Affordable, clinician-reviewed care at your fingertips. Start with a quick assessment, get reviewed by a licensed provider, and receive compounded semaglutide shipped to your door.
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Complete a quick online assessment. Tell us about your health history and weight loss goals to see if you qualify.
A licensed Amie clinician reviews your intake and determines if compounded semaglutide is right for you. 100% online, no video call required.
Your medication ships free in discreet packaging from a licensed US compounding pharmacy, typically within one week.
Compounded semaglutide as low as $151/month. Branded options available with insurance coordination starting at $75/quarter.
In major clinical trials, adults on semaglutide lost around 15% of their body weight on average when paired with lifestyle changes.*
GLP-1 medications are FDA-approved for type 2 diabetes and have demonstrated significant efficacy for weight management in clinical studies.
If appropriate, your Amie clinician prescribes compounded semaglutide tailored to your needs and goals.
Compounded semaglutide from $151/month without insurance. Branded GLP-1s available with insurance coordination starting at $75/quarter.
Your medication ships free in discreet packaging from a licensed US compounding pharmacy directly to your door.
Message your care team anytime through your Amie dashboard. Dose adjustments and questions handled online.
Start low and titrate gradually to minimize side effects. Your provider adjusts your plan based on your response.
No long-term contracts. Pause or cancel your plan whenever you want, no questions asked.
Semaglutide is a GLP-1 receptor agonist that works by mimicking a natural hormone to regulate appetite and blood sugar. An Amie provider will review your assessment and prescribe compounded semaglutide if appropriate.
Available in .25mg, .5mg, 1mg, 2.4mg doses
Enter your height and weight to see if you may qualify
Results from major semaglutide clinical trials and real-world outcomes
Average body weight lost in the STEP clinical trial program over 68 weeks*
More weight loss than diet and exercise alone in controlled studies
Of participants achieved at least 5% weight loss on semaglutide 2.4mg*
*Based on the STEP 1 clinical trial: 68-week, double-blind, placebo-controlled study of 1,961 adults with BMI ≥30 (or ≥27 with weight-related conditions). Treatment was semaglutide 2.4mg once weekly plus lifestyle intervention.
"I was skeptical about online prescriptions, but Amie made it so easy. My provider was thorough, and I started seeing results within the first month. Down 22 lbs in 3 months."Sarah M., verified patient
"The pricing is what sold me. I was paying $400/month elsewhere. Amie got me started at $151/month, and my medication arrives on time every single month."Jennifer R., verified patient
"My biggest regret is that I waited so long to start. The gradual dosing meant almost no side effects for me. I feel like myself again for the first time in years."Laura P., verified patient
Compounded semaglutide is a personalized medication prepared by a licensed compounding pharmacy when prescribed by a clinician. It contains the same active ingredient found in branded GLP-1 medications and is commonly considered by patients looking for an affordable path to GLP-1 care without insurance.
In major clinical trials (STEP program), adults on semaglutide 2.4mg lost an average of 15% of their body weight over 68 weeks when paired with lifestyle changes. Individual results vary based on starting weight, adherence, diet, and exercise.
The most common side effects are gastrointestinal: nausea, diarrhea, vomiting, and constipation. These are usually mild to moderate and tend to improve over time, especially with gradual dose titration. Your Amie provider will work with you to manage any side effects.
Insurance is not required. Compounded semaglutide starts at $151/month without insurance. If you have insurance, our team will coordinate coverage for branded GLP-1 medications like Ozempic, with costs as low as $75/quarter.
Semaglutide is taken once weekly as a subcutaneous injection (a small shot under the skin, typically in the abdomen or thigh). Most patients find it quick and relatively painless. Your provider will guide you through the process.
Most patients begin noticing reduced appetite and some weight loss within the first 2-4 weeks. More significant results typically develop over 3-6 months as the dose is gradually increased to the target level.
Yes. There are no long-term contracts or commitments. You can pause or cancel your plan at any time through your Amie dashboard, no questions asked.
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